7-FLUORO-6-NITRO QUINAZOLINONE
7-Fluoro-6-Nitro-4(H)-Quinazoline
CAS: 162012-69-3
Molecular Formula: C8H4FN3O3
7-FLUORO-6-NITRO QUINAZOLINONE - Names and Identifiers
| Name | 7-Fluoro-6-Nitro-4(H)-Quinazoline |
| Synonyms | 7-Fluoro-6-nitro-1H-quina... 7-FLUORO-6-NITRO QUINAZOLINONE 7-fluoro-6-nitroquinazolin-4-ol 7-Fluoro-6-Nitro-4(H)-Quinazoline 7-fluoro-6-nitroquinazolin-4(1H)-one 7-Fluoro-6-nitro-4-hydroxyquinazoline 6-Nitro-7-Fluoro-4-HydroxyQuinazoline 7-Fluoro-6-nitro-4-hydroxy-quinazoline 7-FLUORO-6-NITRO-4-HYDROXY-QUINAZOLINE 4(1H)-QUINAZOLINONE, 7-FLUORO-6-NITRO- |
| CAS | 162012-69-3 |
| EINECS | 1308068-626-2 |
| InChI | InChI=1/C8H4FN3O3/c9-5-2-6-4(1-7(5)12(14)15)8(13)11-3-10-6/h1-3H,(H,10,11,13) |
7-FLUORO-6-NITRO QUINAZOLINONE - Physico-chemical Properties
| Molecular Formula | C8H4FN3O3 |
| Molar Mass | 209.13 |
| Density | 1.75±0.1 g/cm3(Predicted) |
| Melting Point | 282-285 °C(Solv: acetic acid (64-19-7)) |
| Boling Point | 407.6±55.0 °C(Predicted) |
| Flash Point | 200.3°C |
| Vapor Presure | 7.46E-07mmHg at 25°C |
| Appearance | White-like to yellowish solid |
| pKa | -2.69±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.713 |
7-FLUORO-6-NITRO QUINAZOLINONE - Risk and Safety
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
7-FLUORO-6-NITRO QUINAZOLINONE - Reference Information
| Uses | 7-fluoro-6-nitroquinazolin-4 (3H)-1 is an intermediate for the preparation of kinase inhibitors (such as ATP site inhibitors of tyrosine kinase activity of epidermal growth factor receptors). 7-fluoro-6-nitro-4-(hydrogen)-quinazolinone is an intermediate in organic synthesis and pharmaceutical research and development. It is also an intermediate in anti-tumor drugs that can be used to synthesize afatinib. |
Last Update：2024-04-10 22:29:15
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View History
7-FLUORO-6-NITRO QUINAZOLINONE
SOYASAPONIN III
1-Glyceryl stearate
Calcium carbide
ZR COXFFF
Pigment Permanent Violet HB-197
Thiazol Yellow G
SOYASAPONIN III
1-Glyceryl stearate
Calcium carbide
ZR COXFFF
Pigment Permanent Violet HB-197
Thiazol Yellow G